Sound Treatment for Brain Disorders

https://pubmed.ncbi.nlm.nih.gov/28544507/: The Effect of Binaural Beat Technology on the Cardiovascular Stress Response in Military Service Members With Post deployment Stress

Conclusions: When placed under an acute stressor, participants who used music with embedded BBT showed a decrease in sympathetic responses and an increase in parasympathetic responses, while participants who used music alone had the opposite effect.

Clinical relevance: The use of BBT in the theta brainwave frequency embedded into music decreases physical and psychological indications of stress. BBT embedded with beta and delta frequencies may improve cognitive functioning and sleep quality, respectively.

Keywords: Binaural beat technology; heart rate variability; military; post deployment stress

Professor Li-Huei Tsai is the Director of the Picower Institute for Learning and Memory at the Massachusetts Institute of Technology, a Picower Professor of Neuroscience, and an Associate Member of the Broad Institute. See her TED Talk to answer “Could we treat Alzheimer’s with light and sound?” (Source: https://www.ted.com/talks/li_huei_tsai_could_we_treat_alzheimer_s_with_light_and_sound)

 

https://pubmed.ncbi.nlm.nih.gov/32940419: High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) improves symptoms and autonomic function for insomnia: A randomized, placebo-controlled clinical trial 

Conclusions: Results of this controlled clinical trial showed clinically relevant reduction of insomnia symptoms with HIRREM, over, and above an active, sham control, with associated, durable improvement in autonomic cardiovascular regulation

https://pubmed.ncbi.nlm.nih.gov/29502530/: Successful use of closed-loop allostatic neurotechnology for post-traumatic stress symptoms in military personnel: self-reported and autonomic improvements 

Conclusions: Service members or veterans showed reductions in symptomatology of PTS, insomnia, depressive mood, and anxiety that were durable through 6 months after the use of a closed-loop allostatic neurotechnology for the auto-calibration of neural oscillations. This study is the first to report increased HRV or BRS after the use of an intervention for service members or veterans with PTS. Ongoing investigations are strongly warranted.

https://pmc.ncbi.nlm.nih.gov/articles/PMC4325896/: The effect of low-frequency sound stimulation on patients with fibromyalgia: A clinical study

Results: Significant improvements were observed with median scores: Fibromyalgia Impact Questionnaire, 81% (P<0.0001); Jenkins Sleep Scale, 90% (P<0.0001); and Pain Disability Index, 49.1% (P<0.0001). Medication dose was reduced in 73.68% of patients and completely discontinued in 26.32%. Time sitting and standing without pain increased significantly (P<0.0001). Cervical muscle range of motion increased from 25% to 75% (P=0.001), while muscle tone changed from hypertonic to normal (P=0.0002).

Conclusion: In the present study, the LFSS treatment showed no adverse effects and patients receiving the LFSS treatment showed statistically and clinically relevant improvement.

https://news.mit.edu/2023/40-hz-vibrations-reduce-alzheimers-pathology-symptoms-mouse-models-0605

https://pubmed.ncbi.nlm.nih.gov/26029120/

https://www.scientificamerican.com/article/sound-waves-can-heal-brain-disorders/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6924256/